Chapter 2213 Fecal Transplantation (Part 2) (Leader Deadwood VIP Plus 2)
"Yeah, I remember that major depressive disorder is a very serious mental illness. It is said to be caused by a combination of genetic and environmental factors, and stress is the main environmental risk factor." Ringer was also skeptical, he Not at all convinced by Dr. Lancer Payne's views and treatment.
"There is still a principle." Although Zheng Ren did not believe that fecal transplantation can treat severe depression, he still said truthfully, "More and more evidence shows that the microbiome is an environmental factor, which can be passed through the microbiota-gut- Brain axes shape the brain, and mice with altered microbiomes often exhibit depression-related behaviors."
"It is said that it is related to the NLRP3 gene." Su Yun added.
"What N?" Linge was stunned.
"Uh..." Zheng Ren found it really difficult to explain clearly. He thought for a while and said, "To put it simply, knock out NLRP3... a certain gene related to depression. The feces of mice are made into capsules and given to patients orally."
"..."
Both Linger and Director Kong were stunned.
Although he has experienced many battles, but now thinking of Huanglong soup, rat droppings... It feels disgusting to think about it. Nowadays, the feces of mice are still taken orally. Can this really cure diseases?
"Director Lin, what kind of expression do you have?" Su Yun was overjoyed, and pretended to look at Ringer seriously, "Eating rat feces, since ancient times."
"I do know that there is a kind of snack for children called mouse droppings. My friends in Jinling are still looking for it all over the world during the New Year and holidays. Unfortunately, the sales are getting less and less."
"The one you are talking about is a snack made of tangerine peel, plum, white sugar, and hawthorn." Su Yun chuckled and said, "One sentence reveals the age. What era is this? Who still eats rat shit."
"Memories, memories."
"There are mouse feces in Chinese medicine, do you know?" Su Yun brought up the topic again as if playing a prank.
"Wulingzhi, the feces of flying squirrels with multiple teeth." Zheng Ren said, "It is mainly used to treat cold air in trusted subordinates, five malnutrition in children, to prevent epidemics, to cure intestinal wind, to benefit Qi channels, and to close the moon in women."
"It's not professional for you to say that..."
"Just know what it means, why are you so professional." Zheng Rendao, "Using feces transplantation to treat severe depression is still in the stage of animal experiments, and I am not optimistic about this kind of animal experiments."
"Is it because it is impossible to tell whether the mouse is really depressed? In fact, through activities, communication, and play, we can still tell." Seeing that Zheng Ren didn't want to talk, Su Yun smiled and went over, continuing to talk about the treatment of depression.
"If you want to treat Clostridium difficile infection, you can try fecal transplantation, but it's extremely risky." Zheng Ren said, "But..."
"Don't talk nonsense, they are looking for American experts to treat them. Do you believe it or not? If you deny it so carelessly, the people from Director Mao's family will kick you out directly?" Su Yun blew a breath, black forehead Fluttering and fluttering.
"Not at all."
"Is there anything wrong with it? I heard that Director Mao is currently in the stage of illness. No matter who he sees, he will hold his hand and say sorry. The memory is very good, and he can talk about every little detail for a long time." Su Yun said.
"Oh? I think my life is worthless, extremely guilty, regretful, helpless, hopeless, and self-defeating. These points are quite consistent with major depressive disorder." Zheng Ren said: "If this is the case, then it's nothing good idea."
Hearing what Zheng Ren said, Linge lowered his head and sighed.
"Tch, are you talking about the DSM-IV-TR diagnostic criteria, or the ICD-10 diagnostic criteria?"
"Neither." Zheng Ren didn't have the slightest thought of arguing with Su Yun today, and he said directly: "I still agree with Director Mei's statement, normal drug treatment. Fecal transplantation, whether it is through the intestines or oral capsules , are likely to induce more and bigger problems.”
"Okay, Boss Zheng, I will reflect your opinion to the courtyard." Linge finally said cautiously.
"For fecal transplantation, there have been many new research findings recently. For example, in a study in the "Cell" magazine in August 2019, Erick Riquelme and Florencia McAllister of the Anderson Cancer Center in the United States found that a small number of long-term survivors of pancreatic cancer patients, tumors significantly more diverse microbes in
"Can fecal transplants cure cancer?" Ringer was surprised.
"It's just a discovery. Whether it works or not will take a long time to study." Zheng Ren said: "It may also be in the wrong direction. Fecal transplantation is a good thing, but I don't think the method in the experimental stage should be used clinically."
"good."
Linge nodded, then stood up, and said, "Boss Zheng, then I will report to the courtyard."
"Director Lin, you said that after Director Mao and her husband repented, her husband was so angry that he slammed the door and left. Is there such a thing?" Su Yun continued to gossip.
Ringer smiled wryly.
"Why do you ask so many questions? It has nothing to do with diagnosis or treatment," Zheng Ren said.
Hearing what Zheng Ren said, Linge smiled apologetically, turned and left.
Zheng Ren then spoke a few words with Director Kong and left the office.
"Boss, do you really think feces transplants are unreliable?" Su Yun asked.
"It's not unreliable, but it takes a long time to study. The treatment of Clostridium difficile has been used clinically, but the mortality rate is very high."
"If you don't use it, the mortality rate will be close to 100%." Su Yun replied directly.
"Who knows, the method of internal medicine treatment has nothing to do with us." Zheng Ren didn't want to think about it, as a good surgeon is enough.
"Boss, the Intervention Department belongs to the Department of Imaging, and it is an auxiliary clinical department." Su Yun's mouth was too much, and he misinterpreted the meaning, directly attacking Zheng Ren's weakness.
Zheng Ren didn't bother to talk to this guy, so he went back to the office and continued to read.
This time he was looking for information about fecal transplants.
If fecal transplantation wants to become a routine clinical treatment, it will not be possible in twenty or thirty years.
Zheng Ren just watched it fresh, and didn't want to study it from beginning to end. Zheng Ren didn't even want to use the skill Eye of Reality, which had been cooled down.
Who knows the scope behind a study, if you use it casually, you may directly drain your energy and pass out.
Once Zheng Ren suffers a loss, he learns to be good. The eye of truth cannot be used casually. Gastric fundus and left gastric artery embolization surgery can be seen at a glance, is it simple after all?
As for fecal transplants...
As an emerging treatment, it involves too many categories. It seems to be found in the treatment of dysbacteriosis, depression, cancer, and diabetes.
There is a lot of information, and the more Zheng Ren read it, the more he gave up the idea of using the eyes of truth to find out. It is so majestic, if you take a look at it, it might not be fainting, but real death.